Permethrin
Permethrin is a synthetic pyrethroid insecticide and antiparasitic agent that acts by disrupting sodium channel function in insect nerve cell membranes, causing paralysis and death of parasites. It is primarily used topically to treat scabies and head lice infestations, and is also employed as a fabric treatment for malaria prevention by repelling and killing mosquitoes.
Molekularmasse
391,3000 g/mol
LogP
6,50
TPSA
35,50 Ų
Lipinski-Regel der Fünf
Bestanden
Therapeutische Bereiche
Wirkmechanismus
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
2D-Struktur
Cite this structure
Embed this structure
SMILES
CC1(C)C(C=C(Cl)Cl)C1C(=O)OCc1cccc(Oc2ccccc2)c1
InChI
InChI=1S/C21H20Cl2O3/c1-21(2)17(12-18(22)23)19(21)20(24)25-13-14-7-6-10-16(11-14)26-15-8-4-3-5-9-15/h3-12,17,19H,13H2,1-2H3
Molecular Formula
C21H20Cl2O3
HBD / HBA
- / 3
Rotierbare Bindungen
7
Schwere Atome
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Häufig gestellte Fragen
Permethrin is a synthetic pyrethroid insecticide and antiparasitic agent that acts by disrupting sodium channel function in insect nerve cell membranes, causing paralysis and death of parasites. It is primarily used topically to treat scabies and head lice infestations, and is also employed as a fabric treatment for malaria prevention by repelling and killing mosquitoes.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Permethrin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1525. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 40326. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
Medizinischer Haftungsausschluss
This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
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