Phenyl Aminosalicylate

CHEMBL1200868 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

229.2 g/mol

LogP

3.2

Phase

4

Phenyl aminosalicylate is an ester of aminosalicylic acid with anti-inflammatory and antimycobacterial properties that was used as a second-line agent in the treatment of tuberculosis. It acts by competitive inhibition of para-aminobenzoic acid incorporation into folate synthesis in mycobacteria, thereby disrupting bacterial folate metabolism.

Molekularmasse

229,2300 g/mol

LogP

3,20

TPSA

72,60 Å²

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

Nc1ccc(C(=O)Oc2ccccc2)c(O)c1

InChI

InChI=1S/C13H11NO3/c14-9-6-7-11(12(15)8-9)13(16)17-10-4-2-1-3-5-10/h1-8,15H,14H2

Molecular Formula

C13H11NO3

HBD / HBA

2 / 4

Rotierbare Bindungen

3

Schwere Atome

17

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Phenyl aminosalicylate is an ester of aminosalicylic acid with anti-inflammatory and antimycobacterial properties that was used as a second-line agent in the treatment of tuberculosis. It acts by competitive inhibition of para-aminobenzoic acid incorporation into folate synthesis in mycobacteria, thereby disrupting bacterial folate metabolism.

Yes, Phenyl Aminosalicylate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200868. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 8609. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C13H11NO3

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.