Probucol

CHEMBL608 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
516.8 g/mol
LogP
11.3
Phase
4

A lipid-lowering medication that reduces LDL (bad) cholesterol levels and has antioxidant properties, though it also lowers HDL (good) cholesterol, which has limited its widespread use. It has been studied for its potential protective effects on blood vessels and is still used in some countries.

Molekularmasse

516,8000 g/mol

LogP

11,30

TPSA

91,10 Ų

Lipinski-Regel der Fünf

Nicht bestanden

Therapeutische Bereiche

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

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SMILES

CC(C)(Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

InChI

InChI=1S/C31H48O2S2/c1-27(2,3)21-15-19(16-22(25(21)32)28(4,5)6)34-31(13,14)35-20-17-23(29(7,8)9)26(33)24(18-20)30(10,11)12/h15-18,32-33H,1-14H3

Molecular Formula

C31H48O2S2

HBD / HBA

2 / 4

Rotierbare Bindungen

8

Schwere Atome

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

A lipid-lowering medication that reduces LDL (bad) cholesterol levels and has antioxidant properties, though it also lowers HDL (good) cholesterol, which has limited its widespread use. It has been studied for its potential protective effects on blood vessels and is still used in some countries.

Yes, Probucol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL608. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 4912. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.