Probucol
A lipid-lowering medication that reduces LDL (bad) cholesterol levels and has antioxidant properties, though it also lowers HDL (good) cholesterol, which has limited its widespread use. It has been studied for its potential protective effects on blood vessels and is still used in some countries.
Peso Molecular
516,8000 g/mol
LogP
11,30
TPSA
91,10 Ų
Regra dos 5 de Lipinski
Reprovado
Áreas Terapêuticas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Estrutura 2D
Cite this structure
Embed this structure
SMILES
CC(C)(Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1
InChI
InChI=1S/C31H48O2S2/c1-27(2,3)21-15-19(16-22(25(21)32)28(4,5)6)34-31(13,14)35-20-17-23(29(7,8)9)26(33)24(18-20)30(10,11)12/h15-18,32-33H,1-14H3
Molecular Formula
C31H48O2S2
HBD / HBA
2 / 4
Ligações Rotacionáveis
8
Átomos Pesados
35
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Perguntas frequentes
A lipid-lowering medication that reduces LDL (bad) cholesterol levels and has antioxidant properties, though it also lowers HDL (good) cholesterol, which has limited its widespread use. It has been studied for its potential protective effects on blood vessels and is still used in some countries.
Yes, Probucol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL608. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 4912. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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