Propiomazine

CHEMBL1201210 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

340.5 g/mol

LogP

4.8

Phase

4

Propiomazine is a phenothiazine derivative with sedative, anxiolytic, and antihistamine properties that blocks histamine H1 receptors, dopamine receptors, and muscarinic receptors to produce sedation and reduce anxiety. It is used as a premedication for anesthesia, for the short-term management of insomnia, and for sedation during minor procedures.

Molekularmasse

340,5000 g/mol

LogP

4,80

TPSA

48,90 Å²

Lipinski-Regel der Fünf

Bestanden

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

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SMILES

CCC(=O)c1ccc2c(c1)N(CC(C)N(C)C)c1ccccc1S2

InChI

InChI=1S/C20H24N2OS/c1-5-18(23)15-10-11-20-17(12-15)22(13-14(2)21(3)4)16-8-6-7-9-19(16)24-20/h6-12,14H,5,13H2,1-4H3

Molecular Formula

C20H24N2OS

HBD / HBA

- / 4

Rotierbare Bindungen

5

Schwere Atome

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Propiomazine is a phenothiazine derivative with sedative, anxiolytic, and antihistamine properties that blocks histamine H1 receptors, dopamine receptors, and muscarinic receptors to produce sedation and reduce anxiety. It is used as a premedication for anesthesia, for the short-term management of insomnia, and for sedation during minor procedures.

Yes, Propiomazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201210. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4940. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C20H24N2OS

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.