Sorbitol

CHEMBL1682 Phase 4 Zugelassen Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

182.2 g/mol

LogP

-3.1

Phase

4

Sorbitol is a sugar alcohol used as an osmotic laxative, diuretic, humectant, and sweetener in pharmaceutical formulations, and as a vehicle in oral medications and liquid dosage forms. As an osmotic laxative, it draws water into the intestinal lumen to soften stool and stimulate bowel movements, used for constipation and bowel preparation. It is also used as a renal excipient in certain dialysis procedures and as an oral sweetener in diabetic formulations since it is poorly absorbed.

Molekularmasse

182,1700 g/mol

LogP

-3,10

TPSA

121,00 Å²

Lipinski-Regel der Fünf

Bestanden

Therapeutische Bereiche

Glaucoma Cardiovascular Disease Pain Management Generalized Anxiety Disorder Infectious Disease Inflammatory Bowel Disease Systemic Lupus Erythematosus Chronic Kidney Disease Non-Alcoholic Fatty Liver Disease Obesity Type 2 Diabetes Hypertension Breast Cancer Chronic Pain Heart Failure Prostate Cancer Colorectal Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure

Embed this structure

SMILES

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

InChI=1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

Molecular Formula

C6H14O6

HBD / HBA

6 / 6

Rotierbare Bindungen

5

Schwere Atome

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Sorbitol is a sugar alcohol used as an osmotic laxative, diuretic, humectant, and sweetener in pharmaceutical formulations, and as a vehicle in oral medications and liquid dosage forms. As an osmotic laxative, it draws water into the intestinal lumen to soften stool and stimulate bowel movements, used for constipation and bowel preparation. It is also used as a renal excipient in certain dialysis procedures and as an oral sweetener in diabetic formulations since it is poorly absorbed.

Yes, Sorbitol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1682. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5780. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Struktur

Schnelldaten

Formel: C6H14O6
Synonyme: 8

Externe Links

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Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.