Thiothixene Hydrochloride

CHEMBL3989824 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
480.1 g/mol
LogP
Phase
4

Thiothixene hydrochloride is the hydrochloride salt form of thiothixene, a thioxanthene antipsychotic dopamine D2 receptor antagonist. See thiothixene for complete pharmacological details. This salt formulation provides improved water solubility for oral liquid and injectable preparations used in schizophrenia, bipolar disorder, and obesity-related psychiatric management.

Molekularmasse

480,1000 g/mol

TPSA

77,50 Ų

Therapeutische Bereiche

Wirkmechanismus

Competitively binds to its target receptor without activating it, blocking the natural ligand from binding and preventing receptor-mediated signaling.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Competitively binds to its target receptor without activating it, blocking the natural ligand from binding and preventing receptor-mediated signaling.

2D-Struktur

SVG PNG

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SMILES

CN1CCN(CC/C=C2/c3ccccc3Sc3ccc(S(=O)(=O)N(C)C)cc32)CC1.Cl.Cl.O.O

InChI

InChI=1S/C23H29N3O2S2.2ClH.2H2O/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26;;;;/h4-5,7-11,17H,6,12-16H2,1-3H3;2*1H;2*1H2/b19-8-;;;;

Molecular Formula

C23H30ClN3O2S2

HBD / HBA

1 / 6

Rotierbare Bindungen

5

Schwere Atome

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Thiothixene hydrochloride is the hydrochloride salt form of thiothixene, a thioxanthene antipsychotic dopamine D2 receptor antagonist. See thiothixene for complete pharmacological details. This salt formulation provides improved water solubility for oral liquid and injectable preparations used in schizophrenia, bipolar disorder, and obesity-related psychiatric management.

Competitively binds to its target receptor without activating it, blocking the natural ligand from binding and preventing receptor-mediated signaling.

Yes, Thiothixene Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3989824. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 11957704. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.