Triclofos Sodium

CHEMBL1200789 Phase 4 Zugelassen Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
251.4 g/mol
LogP
Phase
4

Triclofos sodium is the sodium salt form of triclofos, a sedative-hypnotic prodrug converted to trichloroethanol in vivo to produce CNS depression through GABA-A potentiation. See triclofos for complete pharmacological details. This salt formulation provides improved solubility for oral liquid preparations used in pediatric sedation.

Molekularmasse

251,3600 g/mol

TPSA

69,60 Ų

Wirkmechanismus

Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanismus

Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.

2D-Struktur

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SMILES

O=P([O-])(O)OCC(Cl)(Cl)Cl.[Na+]

InChI

InChI=1S/C2H4Cl3O4P.Na/c3-2(4,5)1-9-10(6,7)8;/h1H2,(H2,6,7,8);/q;+1/p-1

Molecular Formula

C2H3Cl3NaO4P

HBD / HBA

1 / 4

Rotierbare Bindungen

2

Schwere Atome

11

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Häufig gestellte Fragen

Triclofos sodium is the sodium salt form of triclofos, a sedative-hypnotic prodrug converted to trichloroethanol in vivo to produce CNS depression through GABA-A potentiation. See triclofos for complete pharmacological details. This salt formulation provides improved solubility for oral liquid preparations used in pediatric sedation.

Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.

Yes, Triclofos Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200789. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 23677832. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medizinischer Haftungsausschluss

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.