Triclofos Sodium
Triclofos sodium is the sodium salt form of triclofos, a sedative-hypnotic prodrug converted to trichloroethanol in vivo to produce CNS depression through GABA-A potentiation. See triclofos for complete pharmacological details. This salt formulation provides improved solubility for oral liquid preparations used in pediatric sedation.
Moleküler Ağırlık
251,3600 g/mol
TPSA
69,60 Ų
Etki Mekanizması
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
2D Yapı
Cite this structure
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SMILES
O=P([O-])(O)OCC(Cl)(Cl)Cl.[Na+]
InChI
InChI=1S/C2H4Cl3O4P.Na/c3-2(4,5)1-9-10(6,7)8;/h1H2,(H2,6,7,8);/q;+1/p-1
Molecular Formula
C2H3Cl3NaO4P
HBD / HBA
1 / 4
Döndürülebilir Bağlar
2
Ağır Atomlar
11
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Sıkça Sorulan Sorular
Triclofos sodium is the sodium salt form of triclofos, a sedative-hypnotic prodrug converted to trichloroethanol in vivo to produce CNS depression through GABA-A potentiation. See triclofos for complete pharmacological details. This salt formulation provides improved solubility for oral liquid preparations used in pediatric sedation.
Administered as an inactive precursor that is metabolically converted to its active form in the body. This prodrug design improves bioavailability, absorption, or targeted delivery compared to the active compound.
Yes, Triclofos Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200789. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 23677832. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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