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Trospium Chloride

CHEMBL3084748 Phase 4 Zugelassen Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
428.0 g/mol
LogP
—
Phase
4

Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

Molekularmasse

428,0000 g/mol

TPSA

46,50 Ų

Therapeutische Bereiche

Chronic Obstructive Pulmonary Disease Alzheimer's Disease Schizophrenia Bipolar Disorder Obesity

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D-Struktur

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
O=C(O[C@H]1C[C@H]2CC[C@@H](C1)[N+]21CCCC1)C(O)(c1ccccc1)c1ccccc1.[Cl-]

                

                

                
                

                    
InChI

                    
InChI=1S/C25H30NO3.ClH/c27-24(25(28,19-9-3-1-4-10-19)20-11-5-2-6-12-20)29-23-17-21-13-14-22(18-23)26(21)15-7-8-16-26;/h1-6,9-12,21-23,28H,7-8,13-18H2;1H/q+1;/p-1/t21-,22+,23+;

                

                

                

                    
                    

                        
Molecular Formula

                        
C25H30ClNO3

                    

                    
                    

                        
HBD / HBA

                        
1 / 4

                    

                    
                    

                        
Rotierbare Bindungen

                        
5

                    

                    
                    
                    

                        
Schwere Atome

                        
30

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Häufig gestellte Fragen

                

                    
                    

                        
                        

                            
Trospium chloride is the chloride salt form of trospium, a quaternary ammonium antimuscarinic used for overactive bladder syndrome by selectively blocking M3 muscarinic receptors in bladder smooth muscle. It reduces detrusor overactivity, decreasing urinary urgency, frequency, and incontinence episodes. The quaternary ammonium structure minimizes blood-brain barrier penetration, offering a favorable CNS safety profile.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Trospium Chloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL3084748.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5284631.
                Chemical information database.
            
        
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Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
Medizinischer Haftungsausschluss

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.