Half Maximal Inhibitory Concentration (IC50)
IC50The concentration of an inhibitor required to reduce a biological process by 50%. Used for enzyme inhibitors, receptor antagonists, and cytotoxicity assays. Context-dependent and not directly comparable across assays.
Beispiele
- Statin IC50 for HMG-CoA reductase
- Kinase inhibitor IC50 panels
- Antimicrobial IC50
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The concentration of an inhibitor required to reduce a biological process by 50%. Used for enzyme inhibitors, receptor antagonists, and cytotoxicity assays. Context-dependent and not directly comparable across assays.