Tachyphylaxis

Pharmacodynamics

Rapid decrease in drug response after repeated administration over a short period. Distinguished from tolerance by its acute onset. Often involves depletion of neurotransmitter stores.

Beispiele

  • Indirect sympathomimetics (ephedrine)
  • Nitrate tolerance
  • Nicotine (acute)

Wussten Sie schon?

Rapid decrease in drug response after repeated administration over a short period. Distinguished from tolerance by its acute onset. Often involves depletion of neurotransmitter stores.