Time to Maximum Concentration (Tmax)

Tmax
Pharmacokinetics

The time elapsed between drug administration and the point of maximum plasma concentration (Cmax). Reflects the rate of absorption and is independent of dose for linear PK systems.

Beispiele

  • Tmax delayed by food
  • ER formulations have later Tmax
  • IV bolus: Tmax = 0

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The time elapsed between drug administration and the point of maximum plasma concentration (Cmax). Reflects the rate of absorption and is independent of dose for linear PK systems.