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Acamprosate

CHEMBL1201293 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
181.2 g/mol
LogP
-1.2
Phase
4

A medication used to help people who have stopped drinking alcohol remain abstinent by reducing the unpleasant physical and emotional symptoms that can occur during prolonged sobriety. It is thought to restore the brain's chemical balance disrupted by long-term alcohol use, easing feelings of anxiety, restlessness, and discomfort that can trigger relapse. It must be taken consistently three times daily and works best when combined with counseling or a support program.

Molecular Weight

181.2100 g/mol

LogP

-1.20

TPSA

91.90 Ų

Lipinski RO5

Pass

Therapeutic Areas

Bipolar Disorder Generalized Anxiety Disorder Major Depressive Disorder Parkinson's Disease Schizophrenia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CC(=O)NCCCS(=O)(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C5H11NO4S/c1-5(7)6-3-2-4-11(8,9)10/h2-4H2,1H3,(H,6,7)(H,8,9,10)

                

                

                

                    
                    

                        
Molecular Formula

                        
C5H11NO4S

                    

                    
                    

                        
HBD / HBA

                        
2 / 4

                    

                    
                    

                        
Rotatable Bonds

                        
4

                    

                    
                    
                    

                        
Heavy Atoms

                        
11

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Frequently Asked Questions

                

                    
                    

                        
                        

                            
A medication used to help people who have stopped drinking alcohol remain abstinent by reducing the unpleasant physical and emotional symptoms that can occur during prolonged sobriety. It is thought to restore the brain's chemical balance disrupted by long-term alcohol use, easing feelings of anxiety, restlessness, and discomfort that can trigger relapse. It must be taken consistently three times daily and works best when combined with counseling or a support program.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Acamprosate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1201293.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 71158.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medical Disclaimer

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.