Benzbromarone

CHEMBL388590 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

424.1 g/mol

LogP

5.7

Phase

4

A uricosuric agent that increases the excretion of uric acid through the kidneys by blocking its reabsorption, used to lower elevated uric acid levels in gout. It is available in some countries but was withdrawn in others due to rare liver toxicity.

Molecular Weight

424.1000 g/mol

LogP

5.70

TPSA

50.40 Å²

Lipinski RO5

Pass

Therapeutic Areas

Chronic Kidney Disease Gout Heart Failure Hypertension Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1

InChI

InChI=1S/C17H12Br2O3/c1-2-13-15(10-5-3-4-6-14(10)22-13)16(20)9-7-11(18)17(21)12(19)8-9/h3-8,21H,2H2,1H3

Molecular Formula

C17H12Br2O3

HBD / HBA

1 / 3

Rotatable Bonds

3

Heavy Atoms

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A uricosuric agent that increases the excretion of uric acid through the kidneys by blocking its reabsorption, used to lower elevated uric acid levels in gout. It is available in some countries but was withdrawn in others due to rare liver toxicity.

Yes, Benzbromarone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL388590. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 2333. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C17H12Br2O3

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.