Bleomycin Sulfate

CHEMBL6067493 Phase 4 Approved Unknown

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

1513.6 g/mol

LogP

—

Phase

4

The sulfate salt form of bleomycin, an antineoplastic agent that acts by causing DNA strand breaks in cancer cells. It is used in combination chemotherapy regimens for lymphomas and testicular cancers. Pulmonary toxicity and skin reactions are important adverse effects requiring careful monitoring.

Molecular Weight

1513.6000 g/mol

TPSA

768.00 Å²

Therapeutic Areas

Bladder Cancer Breast Cancer Colorectal Cancer HIV/AIDS Leukemia Lymphoma Melanoma Non-Small Cell Lung Cancer Ovarian Cancer Pancreatic Cancer Prostate Cancer Thyroid Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

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SMILES

CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@@H]([C@H](C2=CN=CN2)O[C@H]3[C@H]([C@H]([C@@H]([C@@H](O3)CO)O)O)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O.OS(=O)(=O)O

InChI

InChI=1S/C55H83N17O21S3.H2O4S/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6;1-5(2,3)4/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88);(H2,1,2,3,4)/p+1/t21-,22+,23+,24-,25-,29-,30+,34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,53+,54-;/m0./s1

Molecular Formula

C55H86N17O25S4+

HBD / HBA

22 / 35

Rotatable Bonds

36

Heavy Atoms

101

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

The sulfate salt form of bleomycin, an antineoplastic agent that acts by causing DNA strand breaks in cancer cells. It is used in combination chemotherapy regimens for lymphomas and testicular cancers. Pulmonary toxicity and skin reactions are important adverse effects requiring careful monitoring.

Yes, Bleomycin Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6067493. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 71587153. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C55H86N17O25S4+
Synonyms: 1

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.