Bucetin
An analgesic and antipyretic drug that was used to relieve mild to moderate pain and reduce fever. It belongs to the phenacetin family of compounds and was found to carry risks of kidney damage with prolonged use. It has been withdrawn from the market in most countries due to nephrotoxicity concerns.
Molecular Weight
223.2700 g/mol
LogP
1.80
TPSA
58.60 Ų
Lipinski RO5
Pass
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
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SMILES
CCOc1ccc(NC(=O)CC(C)O)cc1
InChI
InChI=1S/C12H17NO3/c1-3-16-11-6-4-10(5-7-11)13-12(15)8-9(2)14/h4-7,9,14H,3,8H2,1-2H3,(H,13,15)
Molecular Formula
C12H17NO3
HBD / HBA
2 / 3
Rotatable Bonds
5
Heavy Atoms
16
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
An analgesic and antipyretic drug that was used to relieve mild to moderate pain and reduce fever. It belongs to the phenacetin family of compounds and was found to carry risks of kidney damage with prolonged use. It has been withdrawn from the market in most countries due to nephrotoxicity concerns.
Yes, Bucetin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1697856. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 14130. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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