Calfactant
A natural lung surfactant derived from calf lung lavage, used to treat and prevent respiratory distress syndrome in premature newborns. It reduces surface tension in the air sacs of the lungs to keep them from collapsing with each breath. It is instilled directly into the airways of premature infants shortly after birth.
Mechanism of Action
Reduces surface tension at the air-liquid interface in the pulmonary alveoli, preventing alveolar collapse during expiration and improving lung compliance and gas exchange.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Reduces surface tension at the air-liquid interface in the pulmonary alveoli, preventing alveolar collapse during expiration and improving lung compliance and gas exchange.
HBD / HBA
- / -
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A natural lung surfactant derived from calf lung lavage, used to treat and prevent respiratory distress syndrome in premature newborns. It reduces surface tension in the air sacs of the lungs to keep them from collapsing with each breath. It is instilled directly into the airways of premature infants shortly after birth.
Reduces surface tension at the air-liquid interface in the pulmonary alveoli, preventing alveolar collapse during expiration and improving lung compliance and gas exchange.
Yes, Calfactant is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201447. Open-access bioactivity database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.
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