Clidinium
An anticholinergic agent that reduces stomach acid secretion and relieves gastrointestinal muscle spasms by blocking muscarinic receptors. It is often combined with a benzodiazepine to treat irritable bowel syndrome and peptic ulcers.
Molecular Weight
352.4000 g/mol
LogP
3.30
TPSA
46.50 Ų
Lipinski RO5
Pass
Mechanism of Action
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, …
2D Structure
Cite this structure
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SMILES
C[N+]12CCC(CC1)C(OC(=O)C(O)(c1ccccc1)c1ccccc1)C2
InChI
InChI=1S/C22H26NO3/c1-23-14-12-17(13-15-23)20(16-23)26-21(24)22(25,18-8-4-2-5-9-18)19-10-6-3-7-11-19/h2-11,17,20,25H,12-16H2,1H3/q+1
Molecular Formula
C22H26NO3+
HBD / HBA
1 / 3
Rotatable Bonds
5
Heavy Atoms
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
An anticholinergic agent that reduces stomach acid secretion and relieves gastrointestinal muscle spasms by blocking muscarinic receptors. It is often combined with a benzodiazepine to treat irritable bowel syndrome and peptic ulcers.
Enhances the effect of gamma-aminobutyric acid (GABA) at GABA-A receptors by binding to an allosteric site and increasing the frequency of chloride ion channel opening. This produces anxiolytic, sedative, hypnotic, and anticonvulsant effects.
Yes, Clidinium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL620. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2784. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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