Crotamiton
A topical agent with both antiparasitic and antipruritic properties used to treat scabies and relieve itching from various skin conditions. Its precise mechanism of action is not fully established, but it is applied to the skin to kill the Sarcoptes scabiei mite.
Molecular Weight
203.2800 g/mol
LogP
2.80
TPSA
20.30 Ų
Lipinski RO5
Pass
Mechanism of Action
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
2D Structure
Cite this structure
Embed this structure
SMILES
CCN(C1=CC=CC=C1C)C(=O)C=CC
InChI
InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3
Molecular Formula
C13H17NO
HBD / HBA
- / 1
Rotatable Bonds
3
Heavy Atoms
15
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A topical agent with both antiparasitic and antipruritic properties used to treat scabies and relieve itching from various skin conditions. Its precise mechanism of action is not fully established, but it is applied to the skin to kill the Sarcoptes scabiei mite.
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.
Yes, Crotamiton is an approved drug. It has reached clinical phase 4. It is classified as a Unknown.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL6067975. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 2883. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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