Danicopan

CHEMBL4250860 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

580.4 g/mol

LogP

3.3

Phase

4

An oral medication that blocks a complement system protein called factor D, used to treat paroxysmal nocturnal hemoglobinuria in patients who still have significant anemia despite other treatments. It helps reduce the destruction of red blood cells.

Molecular Weight

580.4000 g/mol

LogP

3.30

TPSA

123.00 Å²

Lipinski RO5

Pass

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(-c3cnc(C)nc3)cc12

InChI

InChI=1S/C26H23BrFN7O3/c1-14(36)25-19-8-16(17-10-29-15(2)30-11-17)6-7-20(19)35(33-25)13-24(37)34-12-18(28)9-21(34)26(38)32-23-5-3-4-22(27)31-23/h3-8,10-11,18,21H,9,12-13H2,1-2H3,(H,31,32,38)/t18-,21+/m1/s1

Molecular Formula

C26H23BrFN7O3

HBD / HBA

1 / 8

Rotatable Bonds

6

Heavy Atoms

38

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

An oral medication that blocks a complement system protein called factor D, used to treat paroxysmal nocturnal hemoglobinuria in patients who still have significant anemia despite other treatments. It helps reduce the destruction of red blood cells.

Yes, Danicopan is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4250860. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 118323590. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C26H23BrFN7O3
Synonyms: 1

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.