Dapagliflozin Propanediol
The propanediol co-crystal formulation of dapagliflozin used for type 2 diabetes, heart failure, and chronic kidney disease. The co-crystal improves the solid-state properties of the molecule while maintaining the SGLT2-inhibiting activity of the parent compound.
Molecular Weight
503.0000 g/mol
TPSA
141.00 Ų
Therapeutic Areas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
CCOc1ccc(Cc2cc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1.C[C@H](O)CO.O
InChI
InChI=1S/C21H25ClO6.C3H8O2.H2O/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21;1-3(5)2-4;/h3-8,10,17-21,23-26H,2,9,11H2,1H3;3-5H,2H2,1H3;1H2/t17-,18-,19+,20-,21+;3-;/m10./s1
Molecular Formula
C24H35ClO9
HBD / HBA
7 / 9
Rotatable Bonds
7
Heavy Atoms
34
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
The propanediol co-crystal formulation of dapagliflozin used for type 2 diabetes, heart failure, and chronic kidney disease. The co-crystal improves the solid-state properties of the molecule while maintaining the SGLT2-inhibiting activity of the parent compound.
Yes, Dapagliflozin Propanediol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL2103802. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 24906252. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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