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Deoxycholic Acid

CHEMBL406393 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
392.6 g/mol
LogP
4.9
Phase
4

A naturally occurring bile acid that disrupts and destroys fat cell membranes, used as an injectable treatment to reduce submental fat (the double chin) under the jaw. The destroyed fat cells are permanently eliminated by the body's immune system. Injections can cause swelling, numbness, and bruising, and multiple treatment sessions are typically needed.

Molecular Weight

392.6000 g/mol

LogP

4.90

TPSA

77.80 Ų

Lipinski RO5

Pass

Therapeutic Areas

Atopic Dermatitis Breast Cancer Colorectal Cancer Gastroesophageal Reflux Disease Heart Failure Hepatitis C HIV/AIDS Hyperlipidemia Leukemia Lymphoma Non-Alcoholic Fatty Liver Disease Obesity Rheumatoid Arthritis Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

                

                

                
                

                    
InChI

                    
InChI=1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H40O4

                    

                    
                    

                        
HBD / HBA

                        
3 / 4

                    

                    
                    

                        
Rotatable Bonds

                        
4

                    

                    
                    
                    

                        
Heavy Atoms

                        
28

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Frequently Asked Questions

                

                    
                    

                        
                        

                            
A naturally occurring bile acid that disrupts and destroys fat cell membranes, used as an injectable treatment to reduce submental fat (the double chin) under the jaw. The destroyed fat cells are permanently eliminated by the body's immune system. Injections can cause swelling, numbness, and bruising, and multiple treatment sessions are typically needed.

                        

                    

                    

                    

                    

                    

                    

                        
                        

                            
Yes, Deoxycholic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL406393.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 222528.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medical Disclaimer

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.