Dextromethorphan Polistirex

CHEMBL1201461 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

352.3 g/mol

LogP

—

Phase

4

A polymer-bound extended-release form of dextromethorphan that releases the drug slowly in the gastrointestinal tract, providing longer-lasting cough suppression than standard formulations. It is used in 12-hour cough syrup preparations.

Molecular Weight

352.3000 g/mol

TPSA

12.50 Å²

Therapeutic Areas

Alzheimer's Disease Bipolar Disorder Breast Cancer Chronic Pain Generalized Anxiety Disorder Hypertension Leukemia Lymphoma Major Depressive Disorder Malaria Melanoma Migraine Multiple Sclerosis Obesity Pain Management Parkinson's Disease Prostate Cancer Psoriasis Rheumatoid Arthritis Schizophrenia Stroke Tuberculosis Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

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SMILES

CN1CC[C@@]23CCCC[C@@H]2[C@@H]1CC4=C3C=C(C=C4)OC.Br

InChI

InChI=1S/C18H25NO.BrH/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18;/h6-7,12,15,17H,3-5,8-11H2,1-2H3;1H/t15-,17+,18+;/m1./s1

Molecular Formula

C18H26BrNO

HBD / HBA

1 / 2

Rotatable Bonds

1

Heavy Atoms

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A polymer-bound extended-release form of dextromethorphan that releases the drug slowly in the gastrointestinal tract, providing longer-lasting cough suppression than standard formulations. It is used in 12-hour cough syrup preparations.

Yes, Dextromethorphan Polistirex is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201461. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 5464025. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C18H26BrNO
Synonyms: 24

External Links

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.