Diquafosol Tetrasodium

CHEMBL1767408 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

878.2 g/mol

LogP

—

Phase

4

A tetrasodium salt form of diquafosol used as an eye drop to treat dry eye syndrome. It works by activating receptors on the ocular surface to stimulate tear secretion.

Molecular Weight

878.2000 g/mol

TPSA

405.00 Å²

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

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SMILES

O=c1ccn([C@@H]2O[C@H](COP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OP(=O)([O-])OC[C@H]3O[C@@H](n4ccc(=O)[nH]c4=O)[C@H](O)[C@@H]3O)[C@@H](O)[C@H]2O)c(=O)[nH]1.[Na+].[Na+].[Na+].[Na+]

InChI

InChI=1S/C18H26N4O23P4.4Na/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31,32)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30;;;;/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,19,23,29)(H,20,24,30);;;;/q;4*+1/p-4/t7-,8-,11-,12-,13-,14-,15-,16-;;;;/m1..../s1

Molecular Formula

C18H22N4Na4O23P4

HBD / HBA

6 / 23

Rotatable Bonds

14

Heavy Atoms

53

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A tetrasodium salt form of diquafosol used as an eye drop to treat dry eye syndrome. It works by activating receptors on the ocular surface to stimulate tear secretion.

Yes, Diquafosol Tetrasodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1767408. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 148196. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C18H22N4Na4O23P4

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.