Dobutamine Hydrochloride

CHEMBL1200418 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

337.8 g/mol

LogP

—

Phase

4

The hydrochloride salt form of dobutamine, the standard preparation used in intravenous infusions for the treatment of severe heart failure and cardiac stress testing. It increases the force of heart contractions by stimulating cardiac beta-1 receptors. Continuous ECG monitoring is required during administration.

Molecular Weight

337.8000 g/mol

TPSA

72.70 Å²

Therapeutic Areas

Asthma Bladder Cancer Breast Cancer Cardiovascular Disease Chronic Kidney Disease Chronic Obstructive Pulmonary Disease Heart Failure Hypertension Non-Small Cell Lung Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

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SMILES

CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1.Cl

InChI

InChI=1S/C18H23NO3.ClH/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15;/h4-9,12-13,19-22H,2-3,10-11H2,1H3;1H

Molecular Formula

C18H24ClNO3

HBD / HBA

5 / 4

Rotatable Bonds

7

Heavy Atoms

23

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

The hydrochloride salt form of dobutamine, the standard preparation used in intravenous infusions for the treatment of severe heart failure and cardiac stress testing. It increases the force of heart contractions by stimulating cardiac beta-1 receptors. Continuous ECG monitoring is required during administration.

Yes, Dobutamine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200418. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 65324. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C18H24ClNO3
Synonyms: 2

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.