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Doxycycline Calcium

CHEMBL2364574 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
524.6 g/mol
LogP
—
Phase
4

A calcium salt form of doxycycline, a tetracycline antibiotic used to treat bacterial infections. It works identically to other forms of doxycycline by blocking bacterial protein production.

Molecular Weight

524.6000 g/mol

TPSA

182.00 Ų

Therapeutic Areas

Age-Related Macular Degeneration Alzheimer's Disease Atopic Dermatitis Bladder Cancer Breast Cancer Cardiovascular Disease Chronic Kidney Disease Chronic Obstructive Pulmonary Disease Chronic Pain Colorectal Cancer Glaucoma Heart Failure HIV/AIDS Hyperlipidemia Hypertension Infectious Disease Inflammatory Bowel Disease Insomnia Leukemia Lymphoma Malaria Melanoma Migraine Multiple Sclerosis Non-Small Cell Lung Cancer Obesity Ovarian Cancer Pain Management Pancreatic Cancer Prostate Cancer Rheumatoid Arthritis Thyroid Cancer Tuberculosis Type 2 Diabetes

Mechanism of Action

Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanism

Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

2D Structure

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
C[C@H]1c2cccc([O-])c2C(=O)C2=C(O)[C@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@@H]21.C[C@H]1c2cccc([O-])c2C(=O)C2=C(O)[C@]3(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@@H]21.[Ca+2]

                

                

                
                

                    
InChI

                    
InChI=1S/2C22H24N2O8.Ca/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);/q;;+2/p-2/t2*7-,10+,14+,15-,17-,22-;/m00./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H24Ca2N2O8+4

                    

                    
                    

                        
HBD / HBA

                        
6 / 9

                    

                    
                    

                        
Rotatable Bonds

                        
2

                    

                    
                    
                    

                        
Heavy Atoms

                        
34

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Frequently Asked Questions

                

                    
                    

                        
                        

                            
A calcium salt form of doxycycline, a tetracycline antibiotic used to treat bacterial infections. It works identically to other forms of doxycycline by blocking bacterial protein production.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Doxycycline Calcium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2364574.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 73415789.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medical Disclaimer

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.