Dronedarone

CHEMBL184412 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

556.8 g/mol

LogP

7.2

Phase

4

An antiarrhythmic medication used to reduce the risk of hospitalization in patients with atrial fibrillation or atrial flutter. It works by blocking multiple ion channels in the heart to maintain normal rhythm.

Molecular Weight

556.8000 g/mol

LogP

7.20

TPSA

97.20 Å²

Lipinski RO5

Fail

Therapeutic Areas

Atrial Fibrillation Bladder Cancer Breast Cancer Colorectal Cancer Heart Failure Non-Small Cell Lung Cancer Ovarian Cancer Pancreatic Cancer Prostate Cancer Stroke Thyroid Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CCCCc1oc2ccc(NS(C)(=O)=O)cc2c1C(=O)c1ccc(OCCCN(CCCC)CCCC)cc1

InChI

InChI=1S/C31H44N2O5S/c1-5-8-12-29-30(27-23-25(32-39(4,35)36)15-18-28(27)38-29)31(34)24-13-16-26(17-14-24)37-22-11-21-33(19-9-6-2)20-10-7-3/h13-18,23,32H,5-12,19-22H2,1-4H3

Molecular Formula

C31H44N2O5S

HBD / HBA

1 / 7

Rotatable Bonds

18

Heavy Atoms

39

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

An antiarrhythmic medication used to reduce the risk of hospitalization in patients with atrial fibrillation or atrial flutter. It works by blocking multiple ion channels in the heart to maintain normal rhythm.

Yes, Dronedarone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL184412. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 208898. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C31H44N2O5S
Synonyms: 1

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.