Dydrogesterone

CHEMBL1200853 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

312.4 g/mol

LogP

3.8

Phase

4

A synthetic progestin very similar in structure to natural progesterone, used to treat endometriosis, support pregnancy in early stages, and manage menstrual disorders. It is well tolerated and does not significantly affect other hormone systems.

Molecular Weight

312.4000 g/mol

LogP

3.80

TPSA

34.10 Å²

Lipinski RO5

Pass

Therapeutic Areas

Endometriosis Generalized Anxiety Disorder Heart Failure Rheumatoid Arthritis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

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SMILES

CC(=O)[C@H]1CC[C@H]2[C@@H]3C=CC4=CC(=O)CC[C@@]4(C)[C@@H]3CC[C@]12C

InChI

InChI=1S/C21H28O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h4-5,12,16-19H,6-11H2,1-3H3/t16-,17+,18-,19+,20+,21+/m0/s1

Molecular Formula

C21H28O2

HBD / HBA

- / 2

Rotatable Bonds

1

Heavy Atoms

23

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A synthetic progestin very similar in structure to natural progesterone, used to treat endometriosis, support pregnancy in early stages, and manage menstrual disorders. It is well tolerated and does not significantly affect other hormone systems.

Yes, Dydrogesterone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200853. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9051. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C21H28O2

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.