Eflornithine Hydrochloride

CHEMBL1201037 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

236.6 g/mol

LogP

—

Phase

4

A salt form of eflornithine, this medication blocks an enzyme critical for cell growth in certain cancers and parasites. The hydrochloride form helps with absorption and stability of the active compound.

Molecular Weight

236.6400 g/mol

TPSA

90.30 Å²

Therapeutic Areas

Bladder Cancer Breast Cancer Colorectal Cancer Melanoma Non-Small Cell Lung Cancer Prostate Cancer Type 2 Diabetes

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

Cl.NCCCC(N)(C(=O)O)C(F)F.O

InChI

InChI=1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2

Molecular Formula

C6H15ClF2N2O3

HBD / HBA

5 / 7

Rotatable Bonds

5

Heavy Atoms

14

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A salt form of eflornithine, this medication blocks an enzyme critical for cell growth in certain cancers and parasites. The hydrochloride form helps with absorption and stability of the active compound.

Yes, Eflornithine Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201037. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 441361. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C6H15ClF2N2O3
Synonyms: 3

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.