Estramustine Phosphate Sodium

CHEMBL1200721 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

564.3 g/mol

LogP

—

Phase

4

The sodium salt form of estramustine phosphate, this combination hormonal chemotherapy agent targets prostate cancer cells using both estrogen effects and direct cell-killing activity. The sodium salt form is used in oral capsules.

Molecular Weight

564.3000 g/mol

TPSA

102.00 Å²

Therapeutic Areas

Breast Cancer Leukemia Lymphoma Prostate Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

C[C@]12CC[C@@H]3c4ccc(OC(=O)N(CCCl)CCCl)cc4CC[C@H]3[C@@H]1CC[C@@H]2OP(=O)([O-])[O-].[Na+].[Na+]

InChI

InChI=1S/C23H32Cl2NO6P.2Na/c1-23-9-8-18-17-5-3-16(31-22(27)26(12-10-24)13-11-25)14-15(17)2-4-19(18)20(23)6-7-21(23)32-33(28,29)30;;/h3,5,14,18-21H,2,4,6-13H2,1H3,(H2,28,29,30);;/q;2*+1/p-2/t18-,19-,20+,21+,23+;;/m1../s1

Molecular Formula

C23H30Cl2NNa2O6P

HBD / HBA

- / 6

Rotatable Bonds

7

Heavy Atoms

35

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

The sodium salt form of estramustine phosphate, this combination hormonal chemotherapy agent targets prostate cancer cells using both estrogen effects and direct cell-killing activity. The sodium salt form is used in oral capsules.

Yes, Estramustine Phosphate Sodium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200721. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 444000. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C23H30Cl2NNa2O6P

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.