Exemestane
This medication blocks an enzyme called aromatase that converts other hormones into estrogen, reducing estrogen levels in postmenopausal women to slow the growth of hormone-sensitive breast cancer. It is used to treat estrogen receptor-positive breast cancer.
Molecular Weight
296.4000 g/mol
LogP
3.10
TPSA
34.10 Ų
Lipinski RO5
Pass
Therapeutic Areas
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
C=C1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12
InChI
InChI=1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
Molecular Formula
C20H24O2
HBD / HBA
- / 2
Rotatable Bonds
0
Heavy Atoms
22
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
This medication blocks an enzyme called aromatase that converts other hormones into estrogen, reducing estrogen levels in postmenopausal women to slow the growth of hormone-sensitive breast cancer. It is used to treat estrogen receptor-positive breast cancer.
Yes, Exemestane is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200374. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 60198. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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