Fludarabine Phosphate

CHEMBL1096882 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

365.2 g/mol

LogP

-3.1

Phase

4

This phosphate form of fludarabine is an injectable chemotherapy agent that is converted to its active form in the body to interfere with DNA replication in cancer cells. It is used primarily to treat chronic lymphocytic leukemia and other lymphoid malignancies.

Molecular Weight

365.2100 g/mol

LogP

-3.10

TPSA

186.00 Å²

Lipinski RO5

Pass

Therapeutic Areas

Bladder Cancer Breast Cancer Cardiovascular Disease Colorectal Cancer Gastroesophageal Reflux Disease HIV/AIDS Hypertension Inflammatory Bowel Disease Leukemia Lymphoma Melanoma Multiple Sclerosis Non-Alcoholic Fatty Liver Disease Non-Small Cell Lung Cancer Ovarian Cancer Pancreatic Cancer Prostate Cancer Rheumatoid Arthritis Systemic Lupus Erythematosus Thyroid Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

Nc1nc(F)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](O)[C@@H]1O

InChI

InChI=1S/C10H13FN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21)/t3-,5-,6+,9-/m1/s1

Molecular Formula

C10H13FN5O7P

HBD / HBA

5 / 12

Rotatable Bonds

4

Heavy Atoms

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

This phosphate form of fludarabine is an injectable chemotherapy agent that is converted to its active form in the body to interfere with DNA replication in cancer cells. It is used primarily to treat chronic lymphocytic leukemia and other lymphoid malignancies.

Yes, Fludarabine Phosphate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1096882. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 30751. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C10H13FN5O7P
Synonyms: 1

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.