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Folic Acid

CHEMBL1622 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
441.4 g/mol
LogP
-1.1
Phase
4

This synthetic form of the B vitamin folate is essential for DNA synthesis and cell division, and plays a critical role in preventing neural tube defects during early pregnancy. It is used to treat or prevent folate deficiency and is recommended as a supplement for women of childbearing age.

Molecular Weight

441.4000 g/mol

LogP

-1.10

TPSA

209.00 Ų

Lipinski RO5

Pass

Therapeutic Areas

Age-Related Macular Degeneration Alzheimer's Disease Anesthesiology Asthma Atopic Dermatitis Atrial Fibrillation Benign Prostatic Hyperplasia Bipolar Disorder Bladder Cancer Breast Cancer Cardiovascular Disease Chronic Kidney Disease Chronic Obstructive Pulmonary Disease Chronic Pain Colorectal Cancer Deep Vein Thrombosis / Pulmonary Embolism Dermatology Endocrinology Endometriosis Epilepsy Gastroenterology Gastroesophageal Reflux Disease Generalized Anxiety Disorder Glaucoma Gout Heart Failure Hematology Hepatitis C Hepatology HIV/AIDS Hyperlipidemia Hypertension Immunology Infectious Disease Inflammatory Bowel Disease Insomnia Leukemia Lymphoma Major Depressive Disorder Malaria Melanoma Migraine Multiple Sclerosis Nephrology Neurology Non-Alcoholic Fatty Liver Disease Non-Small Cell Lung Cancer Obesity Obstetrics & Gynecology Oncology Ophthalmology Osteoporosis Ovarian Cancer Pain Management Pancreatic Cancer Parkinson's Disease Prostate Cancer Psoriasis Psychiatry Respiratory Disease Rheumatoid Arthritis Rheumatology Schizophrenia Stroke Systemic Lupus Erythematosus Thyroid Cancer Transplant Medicine Tuberculosis Type 2 Diabetes Urology

Mechanism of Action

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanism

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

2D Structure

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Nc1nc(=O)c2nc(CNc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)cnc2[nH]1

                

                

                
                

                    
InChI

                    
InChI=1S/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C19H19N7O6

                    

                    
                    

                        
HBD / HBA

                        
6 / 10

                    

                    
                    

                        
Rotatable Bonds

                        
9

                    

                    
                    
                    

                        
Heavy Atoms

                        
32

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Frequently Asked Questions

                

                    
                    

                        
                        

                            
This synthetic form of the B vitamin folate is essential for DNA synthesis and cell division, and plays a critical role in preventing neural tube defects during early pregnancy. It is used to treat or prevent folate deficiency and is recommended as a supplement for women of childbearing age.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Folic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1622.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 135398658.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medical Disclaimer

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.