Hexafluorenium Bromide
A bromide salt form of hexafluorenium, an acetylcholinesterase inhibitor used in anesthesia to prolong and enhance the neuromuscular blockade produced by succinylcholine. The bromide salt form is the pharmaceutical preparation used in clinical settings. It allows for dose reduction of succinylcholine while maintaining the desired degree of muscle relaxation.
Molecular Weight
662.5000 g/mol
TPSA
0.00 Ų
Mechanism of Action
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
2D Structure
Cite this structure
Embed this structure
SMILES
C[N+](C)(CCCCCC[N+](C)(C)C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21.[Br-].[Br-]
InChI
InChI=1S/C36H42N2.2BrH/c1-37(2,35-31-21-11-7-17-27(31)28-18-8-12-22-32(28)35)25-15-5-6-16-26-38(3,4)36-33-23-13-9-19-29(33)30-20-10-14-24-34(30)36;;/h7-14,17-24,35-36H,5-6,15-16,25-26H2,1-4H3;2*1H/q+2;;/p-2
Molecular Formula
C36H42Br2N2
HBD / HBA
- / 2
Rotatable Bonds
9
Heavy Atoms
40
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A bromide salt form of hexafluorenium, an acetylcholinesterase inhibitor used in anesthesia to prolong and enhance the neuromuscular blockade produced by succinylcholine. The bromide salt form is the pharmaceutical preparation used in clinical settings. It allows for dose reduction of succinylcholine while maintaining the desired degree of muscle relaxation.
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Yes, Hexafluorenium Bromide is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200933. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 9434. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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