Hydrocortisone Hemisuccinate Anhydrous

CHEMBL977 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

462.5 g/mol

LogP

1.8

Phase

4

A hemisuccinate anhydrous form of hydrocortisone with the same therapeutic properties. A synthetic form of the naturally occurring glucocorticoid cortisol, used to treat a wide range of inflammatory and allergic conditions including asthma, eczema, rheumatoid arthritis, and adrenal insufficiency by suppressing immune and inflammatory responses.

Molecular Weight

462.5000 g/mol

LogP

1.80

TPSA

138.00 Å²

Lipinski RO5

Pass

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure

Embed this structure

SMILES

C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)COC(=O)CCC(=O)O

InChI

InChI=1S/C25H34O8/c1-23-9-7-15(26)11-14(23)3-4-16-17-8-10-25(32,24(17,2)12-18(27)22(16)23)19(28)13-33-21(31)6-5-20(29)30/h11,16-18,22,27,32H,3-10,12-13H2,1-2H3,(H,29,30)/t16-,17-,18-,22+,23-,24-,25-/m0/s1

Molecular Formula

C25H34O8

HBD / HBA

3 / 8

Rotatable Bonds

7

Heavy Atoms

33

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A hemisuccinate anhydrous form of hydrocortisone with the same therapeutic properties. A synthetic form of the naturally occurring glucocorticoid cortisol, used to treat a wide range of inflammatory and allergic conditions including asthma, eczema, rheumatoid arthritis, and adrenal insufficiency by suppressing immune and inflammatory responses.

Yes, Hydrocortisone Hemisuccinate Anhydrous is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL977. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 16623. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

Looking for patient-friendly information?

Hydrocortisone Hemisuccinate Anhydrous on PillFYI

Structure

Quick Data

Formula: C25H34O8

External Links

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.