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Irbesartan Hydrochloride

CHEMBL6068339 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
465.0 g/mol
LogP
—
Phase
4

A salt form of irbesartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure and diabetic kidney disease by relaxing blood vessels and reducing strain on the heart.

Molecular Weight

465.0000 g/mol

TPSA

87.10 Ų

Mechanism of Action

Selective non-competitive angiotensin II type 1 receptor antagonist.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanism

Selective non-competitive angiotensin II type 1 receptor antagonist.

2D Structure

SVG PNG

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SMILES

                    
CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1.Cl

                

                

                
                

                    
InChI

                    
InChI=1S/C25H28N6O.ClH/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23;/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30);1H

                

                

                

                    
                    

                        
Molecular Formula

                        
C25H29ClN6O

                    

                    
                    

                        
HBD / HBA

                        
2 / 5

                    

                    
                    

                        
Rotatable Bonds

                        
7

                    

                    
                    
                    

                        
Heavy Atoms

                        
33

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Frequently Asked Questions

                

                    
                    

                        
                        

                            
A salt form of irbesartan, an angiotensin II receptor blocker (ARB) used to treat high blood pressure and diabetic kidney disease by relaxing blood vessels and reducing strain on the heart.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Selective non-competitive angiotensin II type 1 receptor antagonist.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Irbesartan Hydrochloride is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL6068339.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11568906.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medical Disclaimer

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.