Labetalol

CHEMBL429 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

328.4 g/mol

LogP

3.1

Phase

4

A combined alpha and beta-adrenergic blocker used to treat high blood pressure and hypertensive emergencies, including during pregnancy. It lowers blood pressure by reducing heart rate and relaxing blood vessels simultaneously.

Molecular Weight

328.4000 g/mol

LogP

3.10

TPSA

95.60 Å²

Lipinski RO5

Pass

Therapeutic Areas

Asthma Bipolar Disorder Chronic Kidney Disease Chronic Pain Epilepsy Generalized Anxiety Disorder Heart Failure Hypertension Insomnia Migraine Obesity Pain Management Schizophrenia Stroke

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CC(CCc1ccccc1)NCC(O)c1ccc(O)c(C(N)=O)c1

InChI

InChI=1S/C19H24N2O3/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24)

Molecular Formula

C19H24N2O3

HBD / HBA

4 / 4

Rotatable Bonds

8

Heavy Atoms

24

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A combined alpha and beta-adrenergic blocker used to treat high blood pressure and hypertensive emergencies, including during pregnancy. It lowers blood pressure by reducing heart rate and relaxing blood vessels simultaneously.

Yes, Labetalol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL429. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3869. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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Structure

Quick Data

Formula: C19H24N2O3
Synonyms: 4

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.