Lasofoxifene

CHEMBL328190 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

413.5 g/mol

LogP

6.1

Phase

4

A selective estrogen receptor modulator (SERM) used to treat postmenopausal osteoporosis and being studied for estrogen receptor-positive breast cancer. It selectively blocks or activates estrogen receptors in different tissues.

Molecular Weight

413.5000 g/mol

LogP

6.10

TPSA

32.70 Å²

Lipinski RO5

Pass

Therapeutic Areas

Breast Cancer Osteoporosis

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure

Embed this structure

SMILES

Oc1ccc2c(c1)CC[C@H](c1ccccc1)[C@@H]2c1ccc(OCCN2CCCC2)cc1

InChI

InChI=1S/C28H31NO2/c30-24-11-15-27-23(20-24)10-14-26(21-6-2-1-3-7-21)28(27)22-8-12-25(13-9-22)31-19-18-29-16-4-5-17-29/h1-3,6-9,11-13,15,20,26,28,30H,4-5,10,14,16-19H2/t26-,28+/m1/s1

Molecular Formula

C28H31NO2

HBD / HBA

1 / 3

Rotatable Bonds

6

Heavy Atoms

31

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A selective estrogen receptor modulator (SERM) used to treat postmenopausal osteoporosis and being studied for estrogen receptor-positive breast cancer. It selectively blocks or activates estrogen receptors in different tissues.

Yes, Lasofoxifene is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL328190. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 216416. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

PillFYI

Looking for patient-friendly information?

Lasofoxifene on PillFYI

Structure

Quick Data

Formula: C28H31NO2

External Links

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.