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Losartan Potassium

CHEMBL995 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
461.0 g/mol
LogP
—
Phase
4

The potassium salt form of losartan, the standard pharmaceutical preparation of this ARB antihypertensive drug. It is widely used for hypertension, heart failure, and kidney protection in diabetes.

Molecular Weight

461.0000 g/mol

TPSA

77.70 Ų

Therapeutic Areas

Heart Failure Hypertension

Mechanism of Action

Angiotensin II receptor type 1 antagonist.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanism

Angiotensin II receptor type 1 antagonist.

2D Structure

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[n-]2)cc1.[K+]

                

                

                
                

                    
InChI

                    
InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H22ClKN6O

                    

                    
                    

                        
HBD / HBA

                        
1 / 6

                    

                    
                    

                        
Rotatable Bonds

                        
8

                    

                    
                    
                    

                        
Heavy Atoms

                        
31

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
Frequently Asked Questions

                

                    
                    

                        
                        

                            
The potassium salt form of losartan, the standard pharmaceutical preparation of this ARB antihypertensive drug. It is widely used for hypertension, heart failure, and kidney protection in diabetes.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Angiotensin II receptor type 1 antagonist.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Losartan Potassium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL995.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11751549.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
Medical Disclaimer

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.