Medifoxamine
This antidepressant was investigated in France for its ability to inhibit the reuptake of dopamine and serotonin, potentially offering a novel mechanism for treating depression. It did not receive widespread approval.
Molecular Weight
257.3300 g/mol
LogP
3.80
TPSA
21.70 Ų
Lipinski RO5
Pass
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D Structure
Cite this structure
Embed this structure
SMILES
CN(C)CC(Oc1ccccc1)Oc1ccccc1
InChI
InChI=1S/C16H19NO2/c1-17(2)13-16(18-14-9-5-3-6-10-14)19-15-11-7-4-8-12-15/h3-12,16H,13H2,1-2H3
Molecular Formula
C16H19NO2
HBD / HBA
- / 3
Rotatable Bonds
6
Heavy Atoms
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
This antidepressant was investigated in France for its ability to inhibit the reuptake of dopamine and serotonin, potentially offering a novel mechanism for treating depression. It did not receive widespread approval.
Yes, Medifoxamine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL85231. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 36109. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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