Meropenem
A broad-spectrum carbapenem antibiotic given by injection to treat serious and life-threatening bacterial infections, including pneumonia, meningitis, and abdominal and skin infections. It is typically reserved for infections caused by bacteria resistant to other antibiotics.
Molecular Weight
383.5000 g/mol
LogP
-2.40
TPSA
135.00 Ų
Lipinski RO5
Pass
Therapeutic Areas
Mechanism of Action
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
2D Structure
Cite this structure
Embed this structure
SMILES
C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](C(=O)N(C)C)C3)[C@H](C)[C@H]12
InChI
InChI=1S/C17H25N3O5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4/h7-12,18,21H,5-6H2,1-4H3,(H,24,25)/t7-,8-,9+,10+,11-,12-/m1/s1
Molecular Formula
C17H25N3O5S
HBD / HBA
3 / 7
Rotatable Bonds
5
Heavy Atoms
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
A broad-spectrum carbapenem antibiotic given by injection to treat serious and life-threatening bacterial infections, including pneumonia, meningitis, and abdominal and skin infections. It is typically reserved for infections caused by bacteria resistant to other antibiotics.
Selectively blocks angiotensin II type 1 (AT1) receptors, preventing the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This results in vasodilation, reduced sodium retention, and decreased blood pressure.
Yes, Meropenem is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL127. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 441130. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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