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Mersalyl

CHEMBL1200943 Phase 4 Approved Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
505.8 g/mol
LogP
—
Phase
4

An older mercurial diuretic once used to treat fluid overload and edema associated with heart failure and kidney disease. It is no longer in clinical use due to its potential for mercury toxicity and the availability of safer diuretic medications.

Molecular Weight

505.8500 g/mol

TPSA

88.70 Ų

Mechanism of Action

Inhibits sodium reabsorption in the renal tubules, promoting excretion of sodium, chloride, and water. This reduces extracellular fluid volume and cardiac preload, lowering blood pressure.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanism

Inhibits sodium reabsorption in the renal tubules, promoting excretion of sodium, chloride, and water. This reduces extracellular fluid volume and cardiac preload, lowering blood pressure.

SMILES

COC(CNC(=O)C1=CC=CC=C1OCC(=O)[O-])C[Hg+].[OH-].[Na+]

InChI

InChI=1S/C13H16NO5.Hg.Na.H2O/c1-9(18-2)7-14-13(17)10-5-3-4-6-11(10)19-8-12(15)16;;;/h3-6,9H,1,7-8H2,2H3,(H,14,17)(H,15,16);;;1H2/q;2*+1;/p-2

Molecular Formula

C13H16HgNNaO6

HBD / HBA

2 / 6

Rotatable Bonds

7

Heavy Atoms

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

An older mercurial diuretic once used to treat fluid overload and edema associated with heart failure and kidney disease. It is no longer in clinical use due to its potential for mercury toxicity and the availability of safer diuretic medications.

Inhibits sodium reabsorption in the renal tubules, promoting excretion of sodium, chloride, and water. This reduces extracellular fluid volume and cardiac preload, lowering blood pressure.

Yes, Mersalyl is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1200943. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 9806195. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.