Methicillin

CHEMBL575 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

380.4 g/mol

LogP

1.2

Phase

4

A penicillinase-resistant penicillin antibiotic that was historically used to treat staphylococcal infections, now largely replaced by other antibiotics. It is now primarily used as a reference agent in laboratory testing (e.g., defining MRSA).

Molecular Weight

380.4000 g/mol

LogP

1.20

TPSA

130.00 Å²

Lipinski RO5

Pass

Therapeutic Areas

Atopic Dermatitis Bladder Cancer Breast Cancer Colorectal Cancer Generalized Anxiety Disorder Infectious Disease Inflammatory Bowel Disease Non-Small Cell Lung Cancer Ovarian Cancer Pancreatic Cancer Prostate Cancer Thyroid Cancer

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure

Embed this structure

SMILES

COc1cccc(OC)c1C(=O)N[C@@H]1C(=O)N2[C@@H]1SC(C)(C)[C@@H]2C(=O)O

InChI

InChI=1S/C17H20N2O6S/c1-17(2)12(16(22)23)19-14(21)11(15(19)26-17)18-13(20)10-8(24-3)6-5-7-9(10)25-4/h5-7,11-12,15H,1-4H3,(H,18,20)(H,22,23)/t11-,12+,15-/m1/s1

Molecular Formula

C17H20N2O6S

HBD / HBA

2 / 7

Rotatable Bonds

5

Heavy Atoms

26

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A penicillinase-resistant penicillin antibiotic that was historically used to treat staphylococcal infections, now largely replaced by other antibiotics. It is now primarily used as a reference agent in laboratory testing (e.g., defining MRSA).

Yes, Methicillin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL575. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 6087. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

PillFYI

Looking for patient-friendly information?

Methicillin on PillFYI

Structure

Quick Data

Formula: C17H20N2O6S

External Links

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.