Mezlocillin

CHEMBL1731 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

539.6 g/mol

LogP

-0.2

Phase

4

This broad-spectrum acylureidopenicillin antibiotic was used to treat serious infections caused by gram-negative bacteria, including those affecting the abdomen, urinary tract, and blood. It has been largely replaced by other antibiotics with better stability and activity profiles.

Molecular Weight

539.6000 g/mol

LogP

-0.20

TPSA

207.00 Å²

Lipinski RO5

Pass

Therapeutic Areas

Generalized Anxiety Disorder

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](NC(=O)N3CCN(S(C)(=O)=O)C3=O)c3ccccc3)C(=O)N2[C@H]1C(=O)O

InChI

InChI=1S/C21H25N5O8S2/c1-21(2)14(18(29)30)26-16(28)13(17(26)35-21)22-15(27)12(11-7-5-4-6-8-11)23-19(31)24-9-10-25(20(24)32)36(3,33)34/h4-8,12-14,17H,9-10H2,1-3H3,(H,22,27)(H,23,31)(H,29,30)/t12-,13-,14+,17-/m1/s1

Molecular Formula

C21H25N5O8S2

HBD / HBA

3 / 9

Rotatable Bonds

6

Heavy Atoms

36

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

This broad-spectrum acylureidopenicillin antibiotic was used to treat serious infections caused by gram-negative bacteria, including those affecting the abdomen, urinary tract, and blood. It has been largely replaced by other antibiotics with better stability and activity profiles.

Yes, Mezlocillin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1731. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 656511. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C21H25N5O8S2

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.