Midostaurin

CHEMBL608533 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

570.6 g/mol

LogP

4.8

Phase

4

This targeted therapy blocks multiple abnormal proteins that drive the growth of certain cancer cells, particularly in leukemia and a rare condition called systemic mastocytosis. It is taken by mouth in combination with other chemotherapy drugs.

Molecular Weight

570.6000 g/mol

LogP

4.80

TPSA

77.70 Å²

Lipinski RO5

Pass

Therapeutic Areas

Leukemia

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4

InChI

InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1

Molecular Formula

C35H30N4O4

HBD / HBA

1 / 4

Rotatable Bonds

3

Heavy Atoms

43

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

This targeted therapy blocks multiple abnormal proteins that drive the growth of certain cancer cells, particularly in leukemia and a rare condition called systemic mastocytosis. It is taken by mouth in combination with other chemotherapy drugs.

Yes, Midostaurin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL608533. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 9829523. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C35H30N4O4

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.