Mitoxantrone

CHEMBL58 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

444.5 g/mol

LogP

1.0

Phase

4

This chemotherapy and immunosuppressant drug interferes with DNA replication, causing cancer cells and overactive immune cells to die. It is used to treat certain leukemias, breast cancer, and aggressive forms of multiple sclerosis.

Molecular Weight

444.5000 g/mol

LogP

1.00

TPSA

163.00 Å²

Lipinski RO5

Pass

Therapeutic Areas

Breast Cancer Immunology Multiple Sclerosis Neurology Oncology

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

SVG PNG

Cite this structure

Embed this structure

SMILES

O=C1c2c(O)ccc(O)c2C(=O)c2c(NCCNCCO)ccc(NCCNCCO)c21

InChI

InChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2

Molecular Formula

C22H28N4O6

HBD / HBA

8 / 10

Rotatable Bonds

12

Heavy Atoms

32

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

This chemotherapy and immunosuppressant drug interferes with DNA replication, causing cancer cells and overactive immune cells to die. It is used to treat certain leukemias, breast cancer, and aggressive forms of multiple sclerosis.

Yes, Mitoxantrone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL58. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 4212. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-08-20.

PillFYI

Looking for patient-friendly information?

Mitoxantrone on PillFYI

Structure

Quick Data

Formula: C22H28N4O6

External Links

Cite

BibTeX, APA, MLA, Chicago, IEEE, Harvard

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.