Mivacurium
This short-acting neuromuscular blocking agent relaxes skeletal muscles by blocking nerve signals at the junction between nerves and muscles. It is used during surgery and procedures requiring temporary muscle paralysis and mechanical ventilation.
Molecular Weight
1029.3000 g/mol
LogP
8.70
TPSA
145.00 Ų
Lipinski RO5
Fail
Therapeutic Areas
Mechanism of Action
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
2D Structure
Cite this structure
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SMILES
COc1cc2c(cc1OC)[C@@H](Cc1cc(OC)c(OC)c(OC)c1)[N+](C)(CCCOC(=O)CC/C=C/CCC(=O)OCCC[N+]1(C)CCc3cc(OC)c(OC)cc3[C@H]1Cc1cc(OC)c(OC)c(OC)c1)CC2
InChI
InChI=1S/C58H80N2O14/c1-59(25-21-41-35-47(63-3)49(65-5)37-43(41)45(59)29-39-31-51(67-7)57(71-11)52(32-39)68-8)23-17-27-73-55(61)19-15-13-14-16-20-56(62)74-28-18-24-60(2)26-22-42-36-48(64-4)50(66-6)38-44(42)46(60)30-40-33-53(69-9)58(72-12)54(34-40)70-10/h13-14,31-38,45-46H,15-30H2,1-12H3/q+2/b14-13+/t45-,46-,59?,60?/m1/s1
Molecular Formula
C58H80N2O14+2
HBD / HBA
- / 14
Rotatable Bonds
30
Heavy Atoms
74
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
Frequently Asked Questions
This short-acting neuromuscular blocking agent relaxes skeletal muscles by blocking nerve signals at the junction between nerves and muscles. It is used during surgery and procedures requiring temporary muscle paralysis and mechanical ventilation.
Blocks neuromuscular transmission at the motor end plate by competing with acetylcholine for nicotinic receptor binding sites, producing skeletal muscle relaxation and paralysis.
Yes, Mivacurium is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1182833. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5281042. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.
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