Nadolol

CHEMBL521606 Phase 4 Approved Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

309.4 g/mol

LogP

0.7

Phase

4

This beta-blocker medication is used to treat high blood pressure and angina, and to control abnormal heart rhythms including atrial fibrillation. It works by slowing the heart rate and reducing the force of heart contractions, which lowers blood pressure and decreases the heart's workload.

Molecular Weight

309.4000 g/mol

LogP

0.70

TPSA

82.00 Å²

Lipinski RO5

Pass

Therapeutic Areas

Asthma Heart Failure Hypertension Leukemia Lymphoma Migraine Parkinson's Disease

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D Structure

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SMILES

CC(C)(C)NCC(O)COc1cccc2c1CC(O)C(O)C2

InChI

InChI=1S/C17H27NO4/c1-17(2,3)18-9-12(19)10-22-16-6-4-5-11-7-14(20)15(21)8-13(11)16/h4-6,12,14-15,18-21H,7-10H2,1-3H3

Molecular Formula

C17H27NO4

HBD / HBA

4 / 5

Rotatable Bonds

6

Heavy Atoms

22

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

This beta-blocker medication is used to treat high blood pressure and angina, and to control abnormal heart rhythms including atrial fibrillation. It works by slowing the heart rate and reducing the force of heart contractions, which lowers blood pressure and decreases the heart's workload.

Yes, Nadolol is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL521606. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 39147. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

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Structure

Quick Data

Formula: C17H27NO4

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Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.