Niacin

CHEMBL573 Phase 4 Approved Small molecule
Half-Life
Bioavailability
Protein Binding
Molecular Weight
123.1 g/mol
LogP
0.4
Phase
4

A form of vitamin B3 used both as a nutritional supplement and, at higher doses, as a medication to lower triglycerides and raise HDL (good) cholesterol. It has also been studied for its role in supporting nerve function and skin health.

Molecular Weight

123.1100 g/mol

LogP

0.40

TPSA

50.20 Ų

Lipinski RO5

Pass

Therapeutic Areas

Mechanism of Action

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

Mechanism

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

2D Structure

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SMILES

O=C(O)c1cccnc1

InChI

InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)

Molecular Formula

C6H5NO2

HBD / HBA

1 / 3

Rotatable Bonds

1

Heavy Atoms

9

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

Frequently Asked Questions

A form of vitamin B3 used both as a nutritional supplement and, at higher doses, as a medication to lower triglycerides and raise HDL (good) cholesterol. It has also been studied for its role in supporting nerve function and skin health.

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Yes, Niacin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL573. Open-access bioactivity database.
  • PubChem — National Center for Biotechnology Information (NCBI). CID 938. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.

Medical Disclaimer

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.